Fig. 1From: Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorderThe metabolic consequences of an impaired or lacking SSADH enzyme include the accumulation of the inhibitory neurotransmitters GABA and GHB. GABA- γ-aminobutyrate; GABA-T- GABA Transaminase; GAD- Glutamic Acid Decarboxylase; GHB- γ-hydroxybutyrate; SSADH- Succinic Semialdehyde Dehydrogenase; TCA- Tricarboxylic Acid CycleBack to article page