White matter FA reduction of 22q11DS subjects withVCOMT vs. MCOMT (cluster significance thresholdp = 0.00175) | |||||
MCOMT > VCOMT FA | |||||
Cluster size (number of voxels) | Talairach and Tournoux coordinates | Region/tract | Hemisphere | ||
x | y | z | |||
2721 | −7 | −6 | 26 | Anterior cingulum/frontal lobe/corpus callosum | Bilateral |
Forceps minor/inferior fronto-occipital and uncinate fasciculi/anterior and superior corona radiata | Right | ||||
White matter volume reduction of 22q11DS subjects withVCOMT vs. MCOMT (cluster significance thresholdp = 0.005) | |||||
MCOMT > VCOMT Volume | |||||
Cluster size (number of voxels) | Talairach and Tournoux Coordinates | Region | Hemisphere | ||
x | y | z | |||
212 | −36 | −35 | −2 | Hippocampus and superior/middle/inferior temporal gyri | Left |
374 | 7 | 20 | 6 | Anterior limb of internal capsule | Right |
329 | 25 | −2 | 11 | Retrolenticular limb of internal capsule | Right |
4924 | 8 | −14 | 28 | Cingulum and corpus callosum | Bilateral |
213 | 30 | −36 | 31 | Supramarginal gyrus | Right |