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Figure 3 | Journal of Neurodevelopmental Disorders

Figure 3

From: Methotrexate treatment of FraX fibroblasts results in FMR1 transcription but not in detectable FMR1 protein levels

Figure 3

Quantitative analysis of the methotrexate (MTX) effect on fragile X syndrome (FXS) patient fibroblasts. Patient fibroblasts were treated with 2 μg MTX per ml culture medium for 7, 9, 12 and 14 days. cDNAs were synthesized and real-time PCRs were performed. The relative FMR1-expression of the treated cells is illustrated. The light and the dark grey bars show the results of two separate experiments.

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