From: Associations of HLA alleles with specific language impairment
HLA allele | Number of alleles counted in probands | Number of alleles counted in controls | Frequency in probands | Frequency in controls | Fisher’s exact test P | Relative risk | 95% confidence interval – lower boundary | 95% confidence interval – upper boundary | Effect |
---|---|---|---|---|---|---|---|---|---|
HLA-DRB1 DR10 | 395 | 912 | 0.018 | 0.002 | 0.004 | 2.575 | 1.773 | 3.737 | Risk |
HLA-DQA1*0301 | 453 | 1078 | 0.174 | 0.231 | 0.012 | 0.753 | 0.59 | 0.961 | Protective |
HLA-B B57 | 443 | 1055 | 0.023 | 0.047 | 0.029 | 0.541 | 0.303 | 0.963 | Protective |
HLA-DRB1 DR4 | 395 | 912 | 0.108 | 0.158 | 0.02 | 0.692 | 0.510 | 0.939 | Protective |
HLA-DRB1 DR12* | 395 | 912 | 0.005 | 0.02 | 0.05 | 0.333 | 0.09 | 1.243 | Protective |