From: Updated report on tools to measure outcomes of clinical trials in fragile X syndrome
Domain | Outcome measure | Shorter term | Longer term | Quality of tools |
---|---|---|---|---|
Intellectual quotient | Wechsler_WAIS-IV, WPPSI-IV, WISC-V | Yes | ||
Stanford-Binet 5 | Yes | |||
Multiple cognitive skills | NIH Toolbox Cognitive Battery | Yesa | Yes | |
Adaptive behavior | ||||
Vineland-II | Yes | |||
ILS | Yes | |||
W-ADL | Yes | + [100] | ||
Memory & Learning | ||||
WJ working memory | Yes | Yes | ||
RBANS | Yes | Yes | ||
SB-5 Block Span | Yes | Yes | ||
Executive function | ||||
KiTAP (4 subtests) | Yes | Yes | ||
WJ auditory attention | Yes | Yes | ||
WJ digits reversed | Yes | Yes | ||
Language | ||||
PPVT-4 | Yes | |||
EVT-2 | Yes | + [68] | ||
CELF-5/P2 | Yes | |||
FMP | Yes | |||
ELS | Yes | Yes | ||
Social cognition | ||||
SRS | Yes | Yes | ||
Eye tracking | Yes | Yes | ||
SPPA | ? | ? | ? [89] | |
Academic achievement | ||||
WJ Achievement III | Yes | |||
WIAT-II | Yes |