Comparing ability and norm-referenced scores as clinical trial outcomes for neurodevelopmental disabilities: a simulation study

Table 1 Observed power for GSV and V-scale, summarized across subdomains. Impairment level refers to SD below average, such that 5 corresponds to the most impaired condition

Age range	Impairment level	Subdomains	GSV power	V-scale power	Decrease in power when using V-scale instead of GSV
Age range	Impairment level	Subdomains	Median	Median	Min	Q1	Median	Q3	Max
3–6 years	5	8	0.85	0.24	0.11	0.52	0.60	0.68	0.83
	4	9	0.85	0.73	0.06	0.08	0.12	0.16	0.21
	3	11	0.86	0.77	0.03	0.04	0.06	0.07	0.09
	2	11	0.86	0.82	0.02	0.03	0.03	0.04	0.05
	1	11	0.85	0.83	0.02	0.02	0.03	0.04	0.05
12–16 years	5	9	0.86	0.09	0.15	0.43	0.77	0.82	0.86
	4	9	0.86	0.72	0.09	0.10	0.12	0.15	0.18
	3	9	0.86	0.79	0.03	0.04	0.07	0.10	0.15
	2	9	0.86	0.83	0.02	0.03	0.03	0.08	0.10
	1	9	0.85	0.80	0.02	0.04	0.04	0.04	0.07

ISSN: 1866-1955