Table 6 Brain regions where significant differences in regression coefficient in age correlation was observed between 22q11DS and controls (voxel p = 0.05; cluster p = 0.005)
Area | Brain region | Controls > 22q11DS | 22q11DS > controls | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Coordinates | BA | Voxels (n) | Coordinates | BA | Voxels (n) | ||||||
X | Y | Z | Â | Â | X | Y | Z | Â | Â | ||
Frontal | Inferior frontal gyrus | ||||||||||
Right | 7 | 15 | −18 | 11 | 9 |  |  |  |  |  | |
Left | −22 | 33 | −18 | 11 | 9 | −51 | 0 | 20 | 44 | 6 | |
Middle frontal gyrus | |||||||||||
Right | 11 | 19 | −13 | 25 | 8 |  |  |  |  |  | |
Parietal | Inferior parietal lobule | ||||||||||
Right | 47 | −52 | 42 | 40 | 6 |  |  |  |  |  | |
Postcentral gyrus | |||||||||||
Right | 51 | −19 | 26 | 2 | 10 |  |  |  |  |  | |
Temporal | Superior temporal gyrus | ||||||||||
Right | 58 | −26 | 15 | 42 | 19 |  |  |  |  |  | |
Limbic | Parahippocampal gyrus | ||||||||||
Right | 22 | −33 | −13 | 36 | 7 |  |  |  |  |  | |
Hippocampus | |||||||||||
Right | 29 | −26 | −7 |  | 9 |  |  |  |  |  | |
Sub-lobar | Caudate | ||||||||||
Right | 22 | −22 | 20 |  | 9 |  |  |  |  |  | |
Left |  |  |  |  |  | −11 | 22 | 4 |  | 5 | |
Thalamus | |||||||||||
Left | −7 | −22 | 20 |  | 7 |  |  |  |  |  | |
Brainstem | |||||||||||
Right | 11 | −11 | −7 |  | 7 |  |  |  |  |  | |
Cerebellum | |||||||||||
Left | −4 | −30 | −13 |  | 6 |  |  |  |  |  | |