First Author | Year | Sample Size | Age (years) | Gender | Measure | Findings | |
---|---|---|---|---|---|---|---|
ValVal | Met | ||||||
Pezawas | 2004 | 69 | 42 | M: 34 R: 18-60 | mixed | VBM | Met carriers - Reduced CV in bilateral inferior and middle frontal gyri, left precuneus and superior parietal lobule, right medial frontal, precentral, superior frontal, postcentral gyri. Val homozygotes - Reduced CV in right middle frontal and lingual gyri. |
Agartz | 2006 | 66 | 30 | M: 42 | mixed | Automated lobar CV | No significant effect of genotype |
Nemoto | 2006 | 41 | 68 | M: 36 R: 20-72 | mixed | VBM | Met carriers - reduced CV in left parahippocampal gyrus. |
Varnas | 2008 | 73 | 31 | M: 42 | mixed | Cortical Thickness | Trend towards association between genotype and CV in left frontal (straight gyrus, transverse frontopolar, superior frontal) and right frontal (pars triangularis) cortices. No effect of genotype on regional CT |
Schofield | 2008 | 96 | 59 | M: 32 R: 20-60 | mixed | VBM | No effect of genotype in regional CV |