A functional polymorphism of the brain derived neurotrophic factor gene and cortical anatomy in autism spectrum disorder

Raznahan, Armin; Toro, Roberto; Proitsi, Petra; Powell, John; Paus, Tomas; F. Bolton, Patrick; Murphy, Declan G. M.

doi:10.1007/s11689-009-9012-0

Table 3 Results for analyses of covariance for regional cortical measures

From: A functional polymorphism of the brain derived neurotrophic factor gene and cortical anatomy in autism spectrum disorder

REGION	MEASURE
	VOLUME						SURFACE AREA						THICKNESS
	GROUP		BDNF		G x B		GROUP		BDNF		G x B		GROUP		BDNF		G x B
	F	p	F	p	F	p	F	p	F	p	F	p	F	p	F	p	F	p
BankSTS	4.82	0.03	1.99	0.16	1.59	0.21
CaudAntCing	0.02	0.89	0.61	0.44	*6.31*	*0.01*	0.11	0.74	0.46	0.50	*8.44*	*0.005*	0.00	0.95	0.00	0.99	0.15	0.70
CaudMidFr	4.15	0.05	1.03	0.31	0.73	0.40
Cuneus	0.27	0.60	0.02	0.90	0.14	0.71
Entorhinal	0.30	0.59	0.27	0.60	0.01	0.91
Fusiform	2.97	0.09	0.18	0.67	0.92	0.34
InfPar	4.12	0.05	2.39	0.13	0.06	0.81
InfTemp	0.28	0.60	2.35	0.13	1.99	0.16
IsthCing	2.53	0.12	4.47	0.04	3.34	0.07
LatOccip	5.04	0.03	1.01	0.32	0.43	0.51
LatOrbFr	0.50	0.48	0.23	0.63	*5.25*	*0.03*	0.49	0.49	0.23	0.63	*5.25*	*0.03*	0.51	0.48	0.27	0.61	0.16	0.69
Lingual	1.19	0.28	0.24	0.63	0.14	0.71
MedOrbFr	0.03	0.86	0.63	0.43	1.73	0.19
MidTemp	1.84	0.18	0.22	0.64	0.84	0.36
Parahipp	0.50	0.48	0.92	0.34	4.23	0.04	0.06	0.94	0.68	0.41	2.47	0.12	0.72	0.40	0.64	0.43	0.78	0.38
Paracentral	3.77	0.06	2.76	0.10	1.27	0.27
ParsOperc	0.80	0.37	0.72	0.40	1.05	0.31
ParsOrbit	0.66	0.42	2.58	0.11	*4.77*	*0.03*	0.14	0.71	1.32	0.25	*4.36*	*0.04*	1.29	0.26	1.19	0.28	0.78	0.38
ParsTriang	0.08	0.93	0.07	0.80	*4.17*	*0.05*	0.00	0.99	0.01	0.92	*5.46*	*0.02*	0.12	0.76	0.01	0.94	0.05	0.83
PeriCalc	1.41	0.24	0.15	0.70	0.46	0.50
PostCentral	0.97	0.33	0.00	0.99	0.02	0.90
PostCing	0.52	0.48	0.56	0.46	*4.16*	*0.05*	0.28	0.60	0.28	0.60	*7.40*	*0.008*	0.90	0.37	0.59	0.44	0.35	0.56
PreCentral	3.06	0.09	0.42	0.52	0.0	0.35
Precuneus	3.48	0.07	1.45	0.23	2.33	0.13
RostrAntCing	0.20	0.66	1.40	0.24	0.27	0.61
RostrMidFr	0.18	0.67	0.03	0.87	*4.30*	*0.04*	0.01	0.91	0.05	0.82	*5.30*	*0.02*	0.87	0.36	0.00	0.99	0.34	0.56
SupFr	1.23	0.27	1.82	0.18	0.89	0.35
SupPar	0.20	0.66	0.08	0.79	1.65	0.20
SupTemp	0.17	0.68	0.58	0.45	0.70	0.41
SupraMarg	0.26	0.62	3.33	0.07	0.39	0.54
FrontalPole	0.03	0.87	0.14	0.71	0.07	0.80
TempPole	0.07	0.79	0.82	0.39	0.51	0.48
TransvTemp	0.66	0.42	1.84	0.18	1.11	0.30

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ISSN: 1866-1955

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Journal of Neurodevelopmental Disorders

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