Fig. 3
From: Common circuit defect of excitatory-inhibitory balance in mouse models of autism
Interhemispheric asymmetry of PV-cell deficit in VPA and NL-3 mutant mice. a Representative photomicrographs of PV immunohistochemistry in coronal sections of valproic acid treated (VPA; top) and Neuroligin3 mutant (NL3 MUT; bottom) mice. Note the difference in PV-cells in the two hemispheres. Scale bar: 500 µm. b Interhemispheric PV ratios calculated by dividing PV-cell numbers in the two hemispheres at the same anterior-posterior level (ratio = PV low density/PV high density hemisphere). One-way ANOVA test: *** p < 0.0001; Bonferroni multiple comparison test, p < 0.001; ns = not significant; SAL, saline control; WT, wild-type