Fig. 1

Dlx1 mutants displayed locomotor hyperactivity responses in the open field. Representative overlaid traces for the wild-type control (a), Dlx1^+/− (b), and Dlx1^−/− (c) groups are presented. Dlx1 mutant mice showed significant difference in the mean (± SEM) of distance traveled in periphery of open field (d) and percent of time spent in locomotion (e) in the open field test. Dlx1^+/+, n = 9; Dlx1^+/−, n = 9; Dlx1^−/−, n = 6. * = p < 0.05