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Table 1 Characteristics of the participants across analyses

From: Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction

Analysis Series Participant Groups
Analysis 1: SAS Profiles Typically Developing Group FXS-only FXS + ASD
(n = 21) (n = 33) (n = 18)
(Mean ± SD) (Mean ± SD) (Mean ± SD)
Chronological Age (Years)bc 4.05 ± 1.95 3.99 ± 2.25 8.13 ± 3.55
Vineland Adaptive Behavior Compositeabc 98.7 ± 10.7 62.7 ± 12.1 41.1 ± 13.3
Childhood Autism Rating Scale Totalc N/A 24.8 ± 3.2 34.0 ± 3.7
Analysis 2: Cortisol (n = 63) (n = 53) (n = 11)
(Mean ± SD) (Mean ± SD) (Mean ± SD)
Chronological Age (Years)ab 4.88 ± 1.39 7.5 ± 4.06 7.46 ± 4.16
Vineland Adaptive Behavior Compositeabc 98.7 ± 10.7 55.7 ± 16.0 43.5 ± 13.1
Childhood Autism Rating Scale Totalc N/A 24.8 ± 3.1 33.7 ± 3.3
Analysis 3: Behavior Ratings and Cortisol
Cortisol-SAS (n = 21) (n = 34) (n = 9)
(Mean ± SD) (Mean ± SD) (Mean ± SD)
Chronological Age (Years)bc 4.05 ± 1.95 3.99 ± 2.25 8.13 ± 3.55
Vineland Adaptive Behavior Compositeabc 98.7 ± 10.7 62.7 ± 12.1 41.1 ± 13.3
Childhood Autism Rating Scale Total c N/A 24.8 ± 3.2 34.0 ± 3.7
Cortisol-CARS (N/A) (n = 40) (n = 10)
(Mean ± SD) (Mean ± SD) (Mean ± SD)
Chronological Age (Years) N/A 8.03 ± 3.95 7.9 ± 4.1
Vineland Adaptive Behavior Compositec N/A 55.1 ± 13.5 41.0 ± 13.1
Childhood Autism Rating Scale Totalc N/A 24.6 ± 3.1 32.7 ± 2.0
  1. aSignificant difference between Typically Developing Group and FXS-only
  2. bSignificant difference between Typically Developing Group and FXS + ASD
  3. cSignificant difference between FXS-only and FXS + ASD