From: Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction
Analysis Series | Participant Groups | ||
---|---|---|---|
Analysis 1: SAS Profiles | Typically Developing Group | FXS-only | FXS + ASD |
(n = 21) | (n = 33) | (n = 18) | |
(Mean ± SD) | (Mean ± SD) | (Mean ± SD) | |
Chronological Age (Years)^{bc} | 4.05 ± 1.95 | 3.99 ± 2.25 | 8.13 ± 3.55 |
Vineland Adaptive Behavior Composite^{abc} | 98.7 ± 10.7 | 62.7 ± 12.1 | 41.1 ± 13.3 |
Childhood Autism Rating Scale Total^{c} | N/A | 24.8 ± 3.2 | 34.0 ± 3.7 |
Analysis 2: Cortisol | (n = 63) | (n = 53) | (n = 11) |
(Mean ± SD) | (Mean ± SD) | (Mean ± SD) | |
Chronological Age (Years)^{ab} | 4.88 ± 1.39 | 7.5 ± 4.06 | 7.46 ± 4.16 |
Vineland Adaptive Behavior Composite^{abc} | 98.7 ± 10.7 | 55.7 ± 16.0 | 43.5 ± 13.1 |
Childhood Autism Rating Scale Total^{c} | N/A | 24.8 ± 3.1 | 33.7 ± 3.3 |
Analysis 3: Behavior Ratings and Cortisol | |||
Cortisol-SAS | (n = 21) | (n = 34) | (n = 9) |
(Mean ± SD) | (Mean ± SD) | (Mean ± SD) | |
Chronological Age (Years)^{bc} | 4.05 ± 1.95 | 3.99 ± 2.25 | 8.13 ± 3.55 |
Vineland Adaptive Behavior Composite^{abc} | 98.7 ± 10.7 | 62.7 ± 12.1 | 41.1 ± 13.3 |
Childhood Autism Rating Scale Total ^{c} | N/A | 24.8 ± 3.2 | 34.0 ± 3.7 |
Cortisol-CARS | (N/A) | (n = 40) | (n = 10) |
(Mean ± SD) | (Mean ± SD) | (Mean ± SD) | |
Chronological Age (Years) | N/A | 8.03 ± 3.95 | 7.9 ± 4.1 |
Vineland Adaptive Behavior Composite^{c} | N/A | 55.1 ± 13.5 | 41.0 ± 13.1 |
Childhood Autism Rating Scale Total^{c} | N/A | 24.6 ± 3.1 | 32.7 ± 2.0 |