Choline transporter gene variation is associated with attention-deficit hyperactivity disorder

Table 3 FBAT tests for association of the CHT 3’SNP (rs333229) with ADHD and diagnostic subtypes

Diagnosis	N	ADHD (offset = .14)*				Combined (offset = .06)				Inattentive (offset = .08)
Diagnosis	N	Z	P	R²	OR	Z	P	R²	OR	Z	P	R²	OR
Model
Additive	125	-.470	.681	.002	0.86	-1.004	.684	.008	0.72	-.411	.659	.001	0.88
^awith unaffecteds		-.478	.684	.002	0.86	-1.001	.683	.008	0.72	-.285	.612	.001	0.91
Dominant	35	0.179	.479	.00	1.12	0.049	.480	.00	1.03	-.157	.562	.00	0.91
^awith unaffecteds		0.393	.347	.004	1.27	0.314	.376	.003	1.21	0.130	.448	.00	1.08
Recessive	114	-.661	.746	.004	0.80	-1.235	.892	.013	0.66	-.408	.658	.001	0.87
^awith unaffecteds		-.797	.787	.006	0.76	-1.366	.914	.016	0.63	-.422	.663	.002	0.87

N = number of informative families, all tests were interpreted using a one-tailed p-value
^aModels in which ADHD cases were contrasted with unaffected individuals, or in which individuals with the target ADHD subtype were contrasted with both unaffected individuals and individuals diagnosed with the other ADHD subtypes

ISSN: 1866-1955