Table 5 Indications for study in 32 individuals found to have the 16p11.2 microduplication

46,XY,add(11)(p15)

Bilateral tremors

Cerebral palsy

Developmental delay (2)(2) (2)

Developmental delay, ADHD, fetal alcohol syndrome

Developmental delay, autism, mental retardation, tall, thin

Developmental delay, behavior disturbance

Developmental delay, dysmorphic features (2) (2)

Developmental delay, multiple congenital anomalies

Developmental delay, seizure disorder

Developmental delay, seizure disorder, autism

Developmental delay, seizure disorder, autistic disorder

Dysmorphic features

Dysmorphic features, multiple congenital anomalies

Encephalopathy (1) (1)

Failure to thrive

Mental retardation, facial and neck anomalies

Multiple congenital anomalies

Not specified

Seizure disorder

Tracheoesophageal fistula

Thyrotoxicosis

Tremors