|
Not controlled for IQ
|
|
White matter volume deficits in 22q11DS subjects
|
|
Cluster size (number of voxels)
|
Talairach and Tournoux Coordinates
|
Region
|
Hemisphere
|
|
x
|
y
|
z
|
|
4218
|
1
|
−36
|
−11
|
Brainstem/cerebellum
|
Right
|
|
149
|
34
|
−19
|
−9
|
Hippocampus
|
Right
|
|
77
|
−33
|
−35
|
−2
|
Hippocampus
|
Left
|
|
533
|
28
|
−71
|
6
|
Middle occipital gyrus/optic radiation and lingual, middle and inferior occipital gyri/cuneus and precuneus
|
Right
|
|
688
|
8
|
−11
|
23
|
Body, genu and splenium of corpus callosum
|
Inter-hemispheric
|
|
489
|
−12
|
−17
|
52
|
Medial frontal gyrus/paracentral lobule
|
Left
|
|
White matter volume excesses in 22q11DS subjects
|
|
133
|
−8
|
28
|
−15
|
Corpus callosum/cingulum/medial frontal gyrus
|
Left
|
|
459
|
−13
|
5
|
1
|
Globus pallidus/anterior limb and genu of internal capsule
|
Left
|
|
396
|
20
|
1
|
3
|
Putamen/anterior limb and genu of internal capsule
|
Right
|
|
341
|
2
|
−13
|
25
|
Corpus callosum/cingulum
|
Inter-hemispheric
|
|
Controlled for IQ
|
|
White matter volume excesses in 22q11DS subjects
|
|
108
|
3
|
−19
|
−23
|
Brainstem
|
Right
|
|
602
|
−17
|
−12
|
7
|
Posterior limb and genu of internal capsule and superior corona radiata
|
Left
|
|
771
|
23
|
−13
|
8
|
Posterior limb and genu of internal capsule
|
Right
|
|
210
|
22
|
−75
|
19
|
Posterior corona radiata, occipital lobe and superior corona radiata
|
Right
|
|
85
|
−36
|
−2
|
30
|
Pre-central gyrus
|
Left
|
