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Table 4 Concordance of categorical phenotypic variables

From: Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder

 

ADI-R

ADOS

Verbal Comm

Non-verbal Comm

Comm Total

Beh

Dev

Autism Diag

Autism Diag

ASD Diag

Autism Comm

ASD Comm

Autism Social

ASD Social

Autism Comm + Soc

ASD Comm + Soc

ADI-R Social

0.926

0.983

0.945

.907

0.931

0.932

0.792

0.909

0.830

0.917

0.874

0.927

0.815

0.915

ADI-R Verbal Comm

 

No Overlap

1.000

0.900

0.934

0.891

0.732

0.912

0.792

0.926

0.837

0.927

0.759

0.915

ADI-R Non-verbal Comm

  

1.000

0.946

0.988

0.952

0.930

0.968

0.948

0.977

0.957

0.977

0.941

0.971

ADI-R Comm Total

   

0.915

0.952

0.911

0.797

0.930

0.843

0.943

0.876

0.944

0.818

0.933

ADI-R Beh

    

0.917

0.943

0.772

0.901

0.819

0.913

0.842

0.917

0.792

0.907

ADI-R Dev

     

0.876

0.776

0.929

0.825

0.953

0.870

0.953

0.800

0.938

ADI-R Autism Diag

      

0.791

0.877

0.820

0.881

0.846

0.886

0.806

0.880

ADOS Autism Diag

       

0.838

0.946

0.814

0.905

0.811

0.974

0.829

ADOS ASD Diag

        

0.883

0.976

0.919

0.974

0.864

0.991

ADOS Autism Comm

         

0.868

0.878

0.857

0.924

0.879

ADOS ASD Comm

          

0.894

0.961

0.840

0.971

ADOS Autism Social

           

0.907

0.927

0.923

ADOS ASD Social

            

0.838

0.978

ADOS Autism Comm + Soc

             

0.855

  1. Categorical variables are those that are binary (yes/no) for diagnosis or a cutoff threshold
  2. ADI-R Autism Diagnostic Interview-Revised, ADOS Autism Diagnostic Observation Schedule, Comm communication, Beh behavior, Dev development, Diag diagnosis, Soc social