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Table 6 Association of OXTR markers with categorical phenotype cutoff scores on the ADI-R and ADOS (P values)

From: Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder

 

rs2268493 T allele

rs1042778 G allele

rs7632287 G allele

Additive model

Recessive model

Additive model

Recessive model

Additive model

Recessive model

ADI-R

 Autism

 

0.034

  

0.043

0.014

 Social

 

0.025

  

0.034

0.021

 Verbal Comm

    

0.047

0.030

 Non-verbal Comm

0.012

0.033

    

 Comm

 

0.025

  

0.038

0.033

 Behavior

 

0.036

  

0.037

0.022

 Development

 

0.043

  

0.019

0.019

ADOS

 Autism diagnosis

 

0.022

0.048

0.013

0.040

0.006

 ASD diagnosis

 

0.037

 

0.043

0.021

0.007

 Autism Comm Cutoff

 

0.037

  

0.054

0.010

 ASD Comm Cutoff

 

0.038

  

0.030

0.011

 Autism Social Cutoff

 

0.025

 

0.036

0.019

0.004

 ASD Social Cutoff

 

0.021

  

0.013

0.004

 Autism Comm + Social Cutoff

 

0.032

 

0.021

0.028

0.005

 ASD Comm + Social Cutoff

 

0.033

  

0.023

0.008