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Table 3 Receiver operating characteristic analysis of the measured parameters showing area under the curve (AUC), specificity and sensitivity of each.

From: Mechanism of nitrogen metabolism-related parameters and enzyme activities in the pathophysiology of autism

Parameter

AUC

Best cut-off value

Sensitivity, %

Specificity, %

Cr

0.812

0.511

75.0

85.0

NO

0.770

0.036

95.0

55.0

GDH

0.608

1.084

55.0

68.0

ADA

0.624

16.226

80.0

55.0

5'-NT

0.787

10.247

85.0

68.0

NH3

0.586

2.107

25.0

100.0

Urea

0.637

5.196

80.0

50.0

GABA

0.866

61.74

85.0

100.0

Glu:Gln

1.000

0.906

100.0

100.0

  1. aAbbreviations: 5'-NT, 5'-nucleotidase; ADA, adenosine deaminase; Cr, creatine; GABA, gamma-aminobutyric acid; GDH, glutamate dehydrogenase; Gln, glutamine; Glu, glutamate; NH3, ammonia; NO, nitric oxide.