Skip to main content

Table 3 Receiver operating characteristic analysis of the measured parameters showing area under the curve (AUC), specificity and sensitivity of each.

From: Mechanism of nitrogen metabolism-related parameters and enzyme activities in the pathophysiology of autism

Parameter AUC Best cut-off value Sensitivity, % Specificity, %
Cr 0.812 0.511 75.0 85.0
NO 0.770 0.036 95.0 55.0
GDH 0.608 1.084 55.0 68.0
ADA 0.624 16.226 80.0 55.0
5'-NT 0.787 10.247 85.0 68.0
NH3 0.586 2.107 25.0 100.0
Urea 0.637 5.196 80.0 50.0
GABA 0.866 61.74 85.0 100.0
Glu:Gln 1.000 0.906 100.0 100.0
  1. aAbbreviations: 5'-NT, 5'-nucleotidase; ADA, adenosine deaminase; Cr, creatine; GABA, gamma-aminobutyric acid; GDH, glutamate dehydrogenase; Gln, glutamine; Glu, glutamate; NH3, ammonia; NO, nitric oxide.