TY - JOUR AU - Coffee, B. AU - Keith, K. AU - Albizua, I. AU - Malone, T. AU - Mowrey, J. AU - Sherman, S. L. AU - Warren, S. T. PY - 2009 DA - 2009// TI - Incidence of fragile X syndrome by newborn screening for methylated FMR1 DNA JO - Am J Hum Genet VL - 85 UR - https://doi.org/10.1016/j.ajhg.2009.09.007 DO - 10.1016/j.ajhg.2009.09.007 ID - Coffee2009 ER - TY - JOUR AU - Verkerk, A. J. AU - Pieretti, M. AU - Sutcliffe, J. S. AU - Fu, Y. H. AU - Kuhl, D. P. AU - Pizzuti, A. AU - Reiner, O. AU - Richards, S. AU - Victoria, M. F. AU - Zhang, F. P. AU - Eussen, B. E. AU - van Ommen, G. J. B. AU - Blonden, L. A. J. AU - Riggins, G. J. AU - Chastain, J. L. AU - Kunst, C. B. AU - Galjaard, H. AU - Caskey, C. T. AU - Nelson, D. L. AU - Oostra, B. A. AU - Warren, S. T. PY - 1991 DA - 1991// TI - Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome JO - Cell VL - 5 UR - https://doi.org/10.1016/0092-8674(91)90397-H DO - 10.1016/0092-8674(91)90397-H ID - Verkerk1991 ER - TY - JOUR AU - Irwin, S. A. AU - Patel, B. AU - Idupulapati, M. AU - Harris, J. B. AU - Crisostomo, R. A. AU - Larsen, B. P. AU - Kooy, F. AU - Willems, P. J. AU - Cras, P. AU - Kozlowski, P. B. AU - Swain, R. A. AU - Weiler, I. J. AU - Greenough, W. T. PY - 2001 DA - 2001// TI - Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination JO - Am J Med Genet VL - 98 UR - https://doi.org/3.0.CO;2-B DO - 3.0.CO;2-B ID - Irwin2001 ER - TY - JOUR AU - Penzes, P. AU - Cahill, M. E. AU - Jones, K. A. AU - VanLeeuwen, J. E. AU - Woolfrey, K. M. PY - 2011 DA - 2011// TI - Dendritic spine pathology in neuropsychiatric disorders JO - Nat Neurosci VL - 14 UR - https://doi.org/10.1038/nn.2741 DO - 10.1038/nn.2741 ID - Penzes2011 ER - TY - JOUR AU - Sharma, A. AU - Hoeffer, C. A. AU - Takayasu, Y. AU - Miyawaki, T. AU - McBride, S. M. AU - Klann, E. AU - Zukin, R. S. PY - 2010 DA - 2010// TI - Dysregulation of mTOR signaling in fragile X syndrome JO - J Neurosci VL - 30 UR - https://doi.org/10.1523/JNEUROSCI.3696-09.2010 DO - 10.1523/JNEUROSCI.3696-09.2010 ID - Sharma2010 ER - TY - JOUR AU - Osterweil, E. K. AU - Krueger, D. D. AU - Reinhold, K. AU - Bear, M. F. PY - 2010 DA - 2010// TI - Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome JO - J Neurosci VL - 30 UR - https://doi.org/10.1523/JNEUROSCI.3888-10.2010 DO - 10.1523/JNEUROSCI.3888-10.2010 ID - Osterweil2010 ER - TY - JOUR AU - Murphy, M. M. AU - Abbeduto, L. AU - Schroeder, S. AU - Serlin, R. PY - 2007 DA - 2007// TI - Contribution of social and information-processing factors to eye-gaze avoidance in fragile X syndrome JO - Am J Ment Retard VL - 112 UR - https://doi.org/10.1352/0895-8017(2007)112[0349:COSAIF]2.0.CO;2 DO - 10.1352/0895-8017(2007)112[0349:COSAIF]2.0.CO;2 ID - Murphy2007 ER - TY - JOUR AU - Hall, S. S. AU - Burns, D. D. AU - Lightbody, A. A. AU - Reiss, A. L. PY - 2008 DA - 2008// TI - Longitudinal changes in intellectual development in children with Fragile X syndrome JO - J Abnorm Child Psychol VL - 36 UR - https://doi.org/10.1007/s10802-008-9223-y DO - 10.1007/s10802-008-9223-y ID - Hall2008 ER - TY - JOUR AU - Hooper, S. R. AU - Hatton, D. AU - Sideris, J. AU - Sullivan, K. AU - Hammer, J. AU - Schaaf, J. AU - Mirrett, P. AU - Ornstein, P. A. AU - Bailey, D. P. PY - 2008 DA - 2008// TI - Executive functions in young males with fragile X syndrome in comparison to mental age-matched controls: baseline findings from a longitudinal study JO - Neuropsychology VL - 22 UR - https://doi.org/10.1037/0894-4105.22.1.36 DO - 10.1037/0894-4105.22.1.36 ID - Hooper2008 ER - TY - JOUR AU - Bray, S. AU - Hirt, M. AU - Jo, B. AU - Hall, S. S. AU - Lightbody, A. A. AU - Walter, E. AU - Chen, K. AU - Patnaik, S. AU - Reiss, A. L. PY - 2011 DA - 2011// TI - Aberrant frontal lobe maturation in adolescents with fragile X syndrome is related to delayed cognitive maturation JO - Biol Psychiatry VL - 70 UR - https://doi.org/10.1016/j.biopsych.2011.05.038 DO - 10.1016/j.biopsych.2011.05.038 ID - Bray2011 ER - TY - JOUR AU - Hazlett, H. C. AU - Poe, M. D. AU - Lightbody, A. A. AU - Gerig, G. AU - Macfall, J. R. AU - Ross, A. K. AU - Provenzale, J. AU - Martin, A. AU - Reiss, A. L. AU - Piven, J. PY - 2009 DA - 2009// TI - Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism JO - J Neurodev Disord VL - 1 UR - https://doi.org/10.1007/s11689-009-9009-8 DO - 10.1007/s11689-009-9009-8 ID - Hazlett2009 ER - TY - JOUR AU - Hoeft, F. AU - Carter, J. C. AU - Lightbody, A. A. AU - Cody Hazlett, H. AU - Piven, J. AU - Reiss, A. L. PY - 2010 DA - 2010// TI - Region-specific alterations in brain development in one- to three-year-old boys with fragile X syndrome JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1002762107 DO - 10.1073/pnas.1002762107 ID - Hoeft2010 ER - TY - JOUR AU - Provost, J. S. AU - Petrides, M. AU - Monchi, O. PY - 2010 DA - 2010// TI - Dissociating the role of the caudate nucleus and dorsolateral prefrontal cortex in the monitoring of events within human working memory JO - Eur J Neurosci VL - 32 UR - https://doi.org/10.1111/j.1460-9568.2010.07333.x DO - 10.1111/j.1460-9568.2010.07333.x ID - Provost2010 ER - TY - JOUR AU - Hoeft, F. AU - Hernandez, A. AU - Parthasarathy, S. AU - Watson, C. L. AU - Hall, S. S. AU - Reiss, A. L. PY - 2007 DA - 2007// TI - Fronto-striatal dysfunction and potential compensatory mechanisms in male adolescents with fragile X syndrome JO - Hum Brain Mapp VL - 28 UR - https://doi.org/10.1002/hbm.20406 DO - 10.1002/hbm.20406 ID - Hoeft2007 ER - TY - JOUR AU - Kesler, S. R. AU - Lightbody, A. A. AU - Reiss, A. L. PY - 2009 DA - 2009// TI - Cholinergic dysfunction in fragile X syndrome and potential intervention: a preliminary 1H MRS study JO - Am J Med Genet A VL - 149A UR - https://doi.org/10.1002/ajmg.a.32697 DO - 10.1002/ajmg.a.32697 ID - Kesler2009 ER - TY - JOUR AU - Davidovic, L. AU - Navratil, V. AU - Bonaccorso, C. M. AU - Catania, M. V. AU - Bardoni, B. AU - Dumas, M. E. PY - 2011 DA - 2011// TI - A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model JO - Genome Res VL - 21 UR - https://doi.org/10.1101/gr.116764.110 DO - 10.1101/gr.116764.110 ID - Davidovic2011 ER - TY - JOUR AU - Bear, M. F. AU - Huber, K. M. AU - Warren, S. T. PY - 2004 DA - 2004// JO - Trends Neurosci VL - 27 UR - https://doi.org/10.1016/j.tins.2004.04.009 DO - 10.1016/j.tins.2004.04.009 ID - Bear2004 ER - TY - JOUR AU - Veeraragavan, S. AU - Bui, N. AU - Perkins, J. R. AU - Yuva-Paylor, L. A. AU - Carpenter, R. L. AU - Paylor, R. PY - 2011 DA - 2011// TI - Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome JO - Psychopharmacology (Berl) VL - 217 UR - https://doi.org/10.1007/s00213-011-2276-6 DO - 10.1007/s00213-011-2276-6 ID - Veeraragavan2011 ER - TY - JOUR AU - Thomas, A. M. AU - Bui, N. AU - Perkins, J. R. AU - Yuva-Paylor, L. A. AU - Paylor, R. PY - 2012 DA - 2012// TI - Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome JO - Psychopharmacology (Berl) VL - 219 UR - https://doi.org/10.1007/s00213-011-2375-4 DO - 10.1007/s00213-011-2375-4 ID - Thomas2012 ER - TY - JOUR AU - Lightbody, A. A. AU - Hall, S. S. AU - Reiss, A. L. PY - 2006 DA - 2006// TI - Chronological age, but not FMRP levels, predicts neuropsychological performance in girls with fragile X syndrome JO - Am J Med Genet B Neuropsychiatr Genet VL - 141B UR - https://doi.org/10.1002/ajmg.b.30307 DO - 10.1002/ajmg.b.30307 ID - Lightbody2006 ER - TY - JOUR AU - Gothelf, D. AU - Furfaro, J. A. AU - Hoeft, F. AU - Eckert, M. A. AU - Hall, S. S. AU - O'Hara, R. AU - Erba, H. W. AU - Ringel, J. AU - Hayashi, K. M. AU - Patnaik, S. AU - Golianu, B. AU - Kraemer, H. C. AU - Thompson, P. M. AU - Piven, J. AU - Reiss, A. L. PY - 2008 DA - 2008// TI - Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP) JO - Ann Neurol VL - 63 UR - https://doi.org/10.1002/ana.21243 DO - 10.1002/ana.21243 ID - Gothelf2008 ER - TY - JOUR AU - Eliez, S. AU - Blasey, C. M. AU - Freund, L. S. AU - Hastie, T. AU - Reiss, A. L. PY - 2001 DA - 2001// TI - Brain anatomy, gender and IQ in children and adolescents with fragile X syndrome JO - Brain VL - 124 UR - https://doi.org/10.1093/brain/124.8.1610 DO - 10.1093/brain/124.8.1610 ID - Eliez2001 ER - TY - JOUR AU - Lee, A. D. AU - Leow, A. D. AU - Lu, A. AU - Reiss, A. L. AU - Hall, S. AU - Chiang, M. C. AU - Toga, A. W. AU - Thompson, P. M. PY - 2007 DA - 2007// TI - 3D pattern of brain abnormalities in fragile X syndrome visualized using tensor-based morphometry JO - Neuroimage VL - 34 UR - https://doi.org/10.1016/j.neuroimage.2006.09.043 DO - 10.1016/j.neuroimage.2006.09.043 ID - Lee2007 ER - TY - JOUR AU - Menon, V. AU - Leroux, J. AU - White, C. D. AU - Reiss, A. L. PY - 2004 DA - 2004// TI - Frontostriatal deficits in fragile X syndrome: relation to FMR1 gene expression JO - Proc Natl Acad Sci U S A VL - 101 UR - https://doi.org/10.1073/pnas.0304544101 DO - 10.1073/pnas.0304544101 ID - Menon2004 ER - TY - JOUR AU - Tassone, F. AU - Pan, R. AU - Amiri, K. AU - Taylor, A. K. AU - Hagerman, P. J. PY - 2008 DA - 2008// TI - A rapid polymerase chain reaction-based screening method for identification of all expanded alleles of the fragile X (FMR1) gene in newborn and high-risk populations JO - J Mol Diagn VL - 10 UR - https://doi.org/10.2353/jmoldx.2008.070073 DO - 10.2353/jmoldx.2008.070073 ID - Tassone2008 ER - TY - BOOK AU - Wechsler, D. PY - 1999 DA - 1999// TI - Wechsler Abbreviated Scale of Intelligence PB - The Psychological Corporation CY - San Antonio ID - Wechsler1999 ER - TY - BOOK AU - Wechsler, D. PY - 1991 DA - 1991// TI - Wechsler Intelligence Scale for Children PB - The Psychological Corporation CY - San Antonio ID - Wechsler1991 ER - TY - CHAP AU - Taylor, H. ED - Mash, E. J. ED - Terdal, L. G. PY - 1988 DA - 1988// TI - Learning disabilities BT - Behavioral Assessments of Childhood Disorders PB - Guilford Press CY - New York ID - Taylor1988 ER - TY - JOUR AU - Aman, M. G. AU - Burrow, W. H. AU - Wolford, P. L. PY - 1995 DA - 1995// TI - The aberrant behavior checklist-community: factor validity and effect of subject variables for adults in group homes JO - Am J Ment Retard VL - 100 ID - Aman1995 ER - TY - BOOK AU - Achenbach, T. M. AU - Rescorla, L. A. AU - Achenbach, T. M. AU - Rescorla, L. A. PY - 2003 DA - 2003// TI - Manual for the ASEBA Adult Forms & Profiles PB - University of Vermont, Research Center for Children, Youth, and Families CY - Burlington ID - Achenbach2003 ER - TY - BOOK AU - Achenbach, T. M. PY - 1991 DA - 1991// TI - Manual for the Child Behavior Checklist 4–18 and 1991 Profile PB - University of Vermont, Department of Psychiatry CY - Burlington ID - Achenbach1991 ER - TY - JOUR AU - Dreher, W. AU - Leibfritz, D. PY - 1999 DA - 1999// TI - Detection of homonuclear decoupled in vivo proton NMR spectra using constant time chemical shift encoding: CT-PRESS JO - Magn Reson Imaging VL - 17 UR - https://doi.org/10.1016/S0730-725X(98)00156-8 DO - 10.1016/S0730-725X(98)00156-8 ID - Dreher1999 ER - TY - JOUR AU - Mayer, D. AU - Zahr, N. M. AU - Sullivan, E. V. AU - Pfefferbaum, A. PY - 2007 DA - 2007// TI - In vivo metabolite differences between the basal ganglia and cerebellum of the rat brain detected with proton MRS at 3T JO - Psychiatry Res VL - 154 UR - https://doi.org/10.1016/j.pscychresns.2006.11.005 DO - 10.1016/j.pscychresns.2006.11.005 ID - Mayer2007 ER - TY - JOUR AU - Zahr, N. M. AU - Mayer, D. AU - Pfefferbaum, A. AU - Sullivan, E. V. PY - 2008 DA - 2008// TI - Low striatal glutamate levels underlie cognitive decline in the elderly: evidence from in vivo molecular spectroscopy JO - Cereb Cortex VL - 18 UR - https://doi.org/10.1093/cercor/bhm250 DO - 10.1093/cercor/bhm250 ID - Zahr2008 ER - TY - JOUR AU - Hersch, S. M. AU - Gutekunst, C. A. AU - Rees, H. D. AU - Heilman, C. J. AU - Levey, A. I. PY - 1994 DA - 1994// TI - Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies JO - J Neurosci VL - 14 ID - Hersch1994 ER - TY - JOUR AU - Deng, P. Y. AU - Rotman, Z. AU - Blundon, J. A. AU - Cho, Y. AU - Cui, J. AU - Cavalli, V. AU - Zakharenko, S. S. AU - Klyachko, V. A. PY - 2013 DA - 2013// TI - FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels JO - Neuron VL - 77 UR - https://doi.org/10.1016/j.neuron.2012.12.018 DO - 10.1016/j.neuron.2012.12.018 ID - Deng2013 ER - TY - JOUR AU - Soares, D. P. AU - Law, M. PY - 2009 DA - 2009// TI - Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications JO - Clin Radiol VL - 64 UR - https://doi.org/10.1016/j.crad.2008.07.002 DO - 10.1016/j.crad.2008.07.002 ID - Soares2009 ER - TY - JOUR AU - Robbins, T. W. AU - Murphy, E. R. PY - 2006 DA - 2006// TI - Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition JO - Trends Pharmacol Sci VL - 27 UR - https://doi.org/10.1016/j.tips.2006.01.009 DO - 10.1016/j.tips.2006.01.009 ID - Robbins2006 ER - TY - JOUR AU - Hallahan, B. P. AU - Daly, E. M. AU - Simmons, A. AU - Moore, C. J. AU - Murphy, K. C. AU - Murphy, D. D. PY - 2012 DA - 2012// TI - Fragile X syndrome: a pilot proton magnetic resonance spectroscopy study in premutation carriers JO - J Neurodev Disord VL - 4 UR - https://doi.org/10.1186/1866-1955-4-23 DO - 10.1186/1866-1955-4-23 ID - Hallahan2012 ER - TY - JOUR AU - Tassone, F. AU - Hagerman, R. J. AU - Taylor, A. K. AU - Mills, J. B. AU - Harris, S. W. AU - Gane, L. W. AU - Hagerman, P. J. PY - 2000 DA - 2000// TI - Clinical involvement and protein expression in individuals with the FMR1 premutation JO - Am J Med Genet VL - 91 UR - https://doi.org/3.0.CO;2-V DO - 3.0.CO;2-V ID - Tassone2000 ER - TY - JOUR AU - Bernardi, S. AU - Anagnostou, E. AU - Shen, J. AU - Kolevzon, A. AU - Buxbaum, J. D. AU - Hollander, E. AU - Hof, P. R. AU - Fan, J. PY - 2011 DA - 2011// TI - In vivo 1H-magnetic resonance spectroscopy study of the attentional networks in autism JO - Brain Res VL - 1380 UR - https://doi.org/10.1016/j.brainres.2010.12.057 DO - 10.1016/j.brainres.2010.12.057 ID - Bernardi2011 ER - TY - JOUR AU - Gabis, L. V. AU - Baruch, Y. K. AU - Jokel, A. AU - Raz, R. PY - 2011 DA - 2011// TI - Psychiatric and autistic comorbidity in fragile X syndrome across ages JO - J Child Neurol VL - 26 UR - https://doi.org/10.1177/0883073810395937 DO - 10.1177/0883073810395937 ID - Gabis2011 ER - TY - JOUR AU - Coghlan, S. AU - Horder, J. AU - Inkster, B. AU - Mendez, M. A. AU - Murphy, D. G. AU - Nutt, D. J. PY - 2012 DA - 2012// TI - GABA system dysfunction in autism and related disorders: from synapse to symptoms JO - Neurosci Biobehav Rev VL - 36 UR - https://doi.org/10.1016/j.neubiorev.2012.07.005 DO - 10.1016/j.neubiorev.2012.07.005 ID - Coghlan2012 ER - TY - JOUR AU - Gogolla, N. AU - Leblanc, J. J. AU - Quast, K. B. AU - Südhof, T. C. AU - Fagiolini, M. AU - Hensch, T. K. PY - 2009 DA - 2009// TI - Common circuit defect of excitatory-inhibitory balance in mouse models of autism JO - J Neurodev Disord VL - 1 UR - https://doi.org/10.1007/s11689-009-9023-x DO - 10.1007/s11689-009-9023-x ID - Gogolla2009 ER - TY - JOUR AU - Wang, L. W. AU - Berry-Kravis, E. AU - Hagerman, R. J. PY - 2010 DA - 2010// TI - Fragile X: leading the way for targeted treatments in autism JO - Neurotherapeutics VL - 7 UR - https://doi.org/10.1016/j.nurt.2010.05.005 DO - 10.1016/j.nurt.2010.05.005 ID - Wang2010 ER - TY - JOUR AU - O'Brien, F. M. AU - Page, L. AU - O'Gorman, R. L. AU - Bolton, P. AU - Sharma, A. AU - Baird, G. AU - Daly, E. AU - Hallahan, B. AU - Conroy, R. M. AU - Foy, C. AU - Curran, S. AU - Robertson, D. AU - Murphy, K. C. AU - Murphy, D. G. PY - 2010 DA - 2010// TI - Maturation of limbic regions in Asperger syndrome: a preliminary study using proton magnetic resonance spectroscopy and structural magnetic resonance imaging JO - Psychiatry Res VL - 184 UR - https://doi.org/10.1016/j.pscychresns.2010.08.007 DO - 10.1016/j.pscychresns.2010.08.007 ID - O'Brien2010 ER - TY - JOUR AU - Ipser, J. C. AU - Syal, S. AU - Bentley, J. AU - Adnams, C. M. AU - Steyn, B. AU - Stein, D. J. PY - 2012 DA - 2012// TI - 1H-MRS in autism spectrum disorders: a systematic meta-analysis JO - Metab Brain Dis VL - 27 UR - https://doi.org/10.1007/s11011-012-9293-y DO - 10.1007/s11011-012-9293-y ID - Ipser2012 ER - TY - JOUR AU - Ross, A. J. AU - Sachdev, P. S. PY - 2004 DA - 2004// TI - Magnetic resonance spectroscopy in cognitive research JO - Brain Res Brain Res Rev VL - 44 UR - https://doi.org/10.1016/j.brainresrev.2003.11.001 DO - 10.1016/j.brainresrev.2003.11.001 ID - Ross2004 ER - TY - JOUR AU - Wang, X. C. AU - Du, X. X. AU - Tian, Q. AU - Wang, J. Z. PY - 2008 DA - 2008// TI - Correlation between choline signal intensity and acetylcholine level in different brain regions of rat JO - Neurochem Res VL - 33 UR - https://doi.org/10.1007/s11064-007-9509-4 DO - 10.1007/s11064-007-9509-4 ID - Wang2008 ER - TY - JOUR AU - Sarter, M. AU - Bruno, J. P. AU - Givens, B. PY - 2003 DA - 2003// TI - Attentional functions of cortical cholinergic inputs: what does it mean for learning and memory? JO - Neurobiol Learn Mem VL - 80 UR - https://doi.org/10.1016/S1074-7427(03)00070-4 DO - 10.1016/S1074-7427(03)00070-4 ID - Sarter2003 ER - TY - JOUR AU - Yiannoutsos, C. T. AU - Nakas, C. T. AU - Navia, B. A. PY - 2008 DA - 2008// TI - Assessing multiple-group diagnostic problems with multi-dimensional receiver operating characteristic surfaces: application to proton MR spectroscopy (MRS) in HIV-related neurological injury JO - Neuroimage VL - 40 UR - https://doi.org/10.1016/j.neuroimage.2007.09.056 DO - 10.1016/j.neuroimage.2007.09.056 ID - Yiannoutsos2008 ER -