Figure 1

Example voxel placement. MRS voxel (black square) displayed on high resolution T1-weighted image for one example participant (from the comparison group). (A) Axial, (B) coronal and (C) sagittal. We placed 1.5 cm isotropic voxels over the head of the right caudate nucleus. Voxels were placed to maximize caudate head tissue. Note: original voxel was positioned on T2-weighted image, but high resolution T1-weighted image is shown here for enhanced resolution in sagittal and coronal planes. A, anterior; I, inferior; L, left; MRS, magnetic resonance spectroscopy; P, posterior; R, right; S, superior.