Aberrant basal ganglia metabolism in fragile X syndrome: a magnetic resonance spectroscopy study

Table 2 Metabolite concentrations

Metabolite concentrations	Group	Mean	SD
NAA/creatine	FXS	1.23	0.15
NAA/creatine	Comparison	1.38	0.24
Glutamate/creatine	FXS	0.19	0.13
Glutamate/creatine	Comparison	0.20	0.11
Choline/creatine^a	FXS	0.78	0.11
Choline/creatine^a	Comparison	0.87	0.14
myo-inositol/creatine	FXS	0.14	0.05
myo-inositol/creatine	Comparison	0.13	0.06
Glx/creatine^a	FXS	0.20	0.10
Glx/creatine^a	Comparison	0.26	0.10
Voxel composition (% total volume)
Grey matter^a	FXS	0.35	0.03
Grey matter^a	Comparison	0.33	0.02
White matter	FXS	0.34	0.04
White matter	Comparison	0.33	0.02
Cerebrospinal fluid (CSF)^a	FXS	0.31	0.06
Cerebrospinal fluid (CSF)^a	Comparison	0.34	0.03

^aSignificant group difference. CSF cerebrospinal fluid, FXS fragile X syndrome, Glx glutamine + glutamate, NAA N-acetylaspartate.

ISSN: 1866-1955