Figure 3

Graphical illustration of significant reductions in gyrification in patients with neurofibromatosis type 1 (NF1). This figure shows an overlay of F-test statistics (with P values indicated by the color bar) where patients with NF1 have lower local gyrification index than typically developing children. Between-group comparisons were performed controlling for intracranial volume. Blue color depicts gyri with significant group differences at P <0.05, not corrected; yellow P <0.01 and orange P <0.005, both surviving correction for multiple comparisons with FDR q = 0.1; red gyri P <0.001, survives correction for multiple comparisons with FDR q <0.05.