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Table 3 Results of analysis of covariance (ANCOVA) in subcortical regions

From: Gyrification, cortical and subcortical morphometry in neurofibromatosis type 1: an uneven profile of developmental abnormalities

Region

Hemisphere

Volume

  

F

P value

DoD

Thalamus

L

6.106

0.021 a

+

R

9.415

0.005 a

+

Caudate

L

3.468

0.074

 

R

6.861

0.015 a

+

Putamen

L

0.610

0.442

 

R

0.335

0.568

 

Pallidum

L

0.344

0.563

 

R

0.023

0.880

 

Hippocampus

L

3.942

0.058

 

R

0.108

0.746

 

Amygdala

L

0.235

0.632

 

R

1.358

0.255

 

Accumbens area

L

1.525

0.228

 

R

3.140

0.089

 

Ventral diencephalon

L

4.242

0.050

 

R

2.748

0.110

 

CC posterior

 

3.676

0.067

 

CC mid-posterior

 

5.587

0.026 a

+

CC central

 

6.004

0.022 a

+

CC mid-anterior

 

8.919

0.006 a

+

CC anterior

 

2.902

0.101

 

Brainstem

 

2.563

0.122

 
  1. Bold represents significant results (P <0.05).
  2. aRepresents significant results after correction for multiple comparisons with FDR (q = 0.1). A plus sign indicate the direction (upwards) of the group difference, + = NF1 > typically developing subjects.
  3. DoD = direction of difference; CC = corpus callosum; L = left; R = right; TIV = total intracranial volume.