Divergent structural brain abnormalities between different genetic subtypes of children with Prader–Willi syndrome

Table 3 Focal cortical grey matter volumes in children with PWS and healthy controls

	PWS				Control		P value between groups	P_corrvalue DEL versus control	P_corrvalue mUPD versus control	P_corrvalue mUPD versus DEL
	DEL		mUPD
	Mean	SD	Mean	SD	Mean	SD
Left entorhinal	0.00153	0.00025	0.00123	0.00039	0.00148	0.00033	0.028	ns	0.127	0.031
Left banks of STS	0.00237	0.00027	0.00217	0.00053	0.00204	0.00032	0.041	0.06	ns	0.142
Right superior parietal	0.01359	0.00127	0.01363	0.00142	0.01163	0.00099	0.002	0.006	0.006	ns
Right lingual	0.00621	0.00072	0.00532	0.00087	0.00584	0.00059	0.032	ns	ns	0.027
Right parahippocampal	0.00162	0.00021	0.00154	0.0003	0.00194	0.00036	0.014	0.11	0.016	ns
Right banks of STS	0.00201	0.00026	0.00237	0.00033	0.00202	0.00045	0.032	ns	0.045	0.091

All measures presented in table are corrected for TIV. P_corr values that did not survive the Bonferroni correction are included. DEL, deletion; mUPD, maternal uniparental disomy; ns, not significant; PWS, Prader–Willi syndrome; SD, standard deviation; STS, superior temporal sulcus; TIV, total intracranial volume.

ISSN: 1866-1955