Protein | Name | Alias | BRDs | Protein functions | Neurodevelopmental disorders | Reference |
---|---|---|---|---|---|---|
BAZ1A | Bromodomain adjacent to zinc finger domain, 1A | ACF1, WALp1, WCRF180 | 1 | Chromatin remodeling factor | Williams syndrome | |
BAZ1B | Bromodomain adjacent to zinc finger domain, 1B | WSTF, WBSCR9 | 1 | Chromatin remodeling factor, transcriptional regulator | Williams syndrome | |
BRD2 | Bromodomain-containing protein 2 | FSH, RING3 | 2 | Increase transcription of E2F- regulated genes | Juvenile myoclonic epilepsy | [8] |
BRD3 | Bromodomain-containing protein 3 | ORFX, RING3L | 2 | Transcription factor | Autism spectrum disorder | |
BRWD3 | Bromodomain and WD repeat-containing protein 3 | BRODL | 2 | Transcription factor | Mental retardation | |
CECR2 | Cat eye syndrome critical region 2 | Â | 1 | Chromatin remodeling factor | Anencephaly | [13] |
CREBBP | CREB-binding protein | CBP, KAT3A | 1 | HAT, transcription factors, transcription initiator | Rubinstein-Taybi syndrome | [14] |
EP300 | E1A-binding protein p300 | p300, KAT3B | 1 | HAT | Rubinstein-Taybi syndrome 2 | [15] |
GCN5L2 | General control of amino acid synthesis 5-like 2 | KAT2A, GCN5 | 1 | HAT | Neural tube defects | [16] |
SMARCA2 | SWI/SNF-related matrix associated anti-dependent regulator of chromatin a2 | BRM, SNF2L2 | 1 | Chromatin remodeling factor | Nicolaides-Baraitser syndrome | [17] |
SMARCA4 | SWI/SNF-related matrix associated actin-dependent regulator of chromatin a4 | BRG1, SNF2L4, SNF2LB | 1 | Chromatin remodeling factor | Mental retardation | [18] |
TAF1 | TAF1 RNA polymerase II, TATA box-binding protein (TBP)-associated factor | TAFII250 | 2 | Transcription initiation | X-linked dystonia-parkinsonism | [19] |