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Table 1 Common genes altered in the adult (P60) brain by different ethanol treatments during neurodevelopment

From: Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure

Accession no.

Gene symbol

Gene name

Chr.

Fold change per treatment timea

    

E 8/11

E 14/16

P 4/7

NM_019816

Aatf

Apoptosis antagonizing transcription factor

11 B5

-1.20

ns

-1.32

NM_001190371

Ankrd29

Ankyrin repeat domain 29

18 A1

-1.24

-1.2

ns

NM_145990

Cdk5rap2

CDK5 regulatory subunit associated protein 2

4 C2

-1.26

NS

-1.26

NM_198019

Cep78

Centrosomal protein 78

19 A

ns

-1.22

-1.37

NM_133840

Clp1

Cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)

2 D

ns

-1.21

-1.2

NM_027468

Cpm

Carboxypeptidase M

10 D2

-1.29

1.28

ns

NM_001163026

Dnajc13

DnaJ (Hsp40) homolog, subfamily C, member 13

9 F1

ns

1.24

-1.21

NM_008929

Dnajc3

DnaJ (Hsp40) homolog, subfamily C, member 3

14 E4

-1.21

ns

-1.38

NM_028133

Egln3

EGL nine homolog 3 (C. elegans)

12 C1

ns

-1.28

1.41

NM_153782

Fam20a

Family with sequence similarity 20, member A

11 E1

-1.24

1.21

ns

NM_010240

Ftl1

Ferritin light chain 1

7 B4

-1.26

ns

-1.51

NM_001166065

Gcnt4

Gcnt4 glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)

13 D1

ns

-1.24

-1.44

NM_011937

Gnpda1

Glucosamine-6-phosphate deaminase 1

18 B3

-1.21

ns

-1.48

NM_001013385

Grm4

Glutamate receptor, metabotropic 4

17 A3

-1.33

ns

-1.38

AK138760

Gtf3c2

General transcription factor IIIC, polypeptide 2, beta

5 B1

-1.33

1.37

ns

NM_010373

Gzme

Granzyme E

14 C3

1.28

-1.21

-1.21

NM_173400

Haus6

HAUS augmin-like complex, subunit 6

4 C4

1.2

ns

-1.42

NM_175256

Heg1

HEG homolog 1 (zebrafish)

16 B3

-1.2

ns

-1.23

NM_178200

Hist1h2bm

Histone cluster 1, H2bm

13 A2-3

ns

1.27

-1.53

NM_175653

Hist1h3c

Histone cluster 1, H3c

13 A2-3

-1.31

ns

-1.3

NM_001024720

Hmcn1

Hemicentin1

1 G1

1.2

ns

-1.28

NM_008296

Hsf1

Heat shock factor 1

15 D3

-1.25

1.22

-1.22

NM_054079

Iltifb

Interleukin 10-related T cell-derived inducible factor beta

10 D2

-1.22

ns

-2.2

NM_201531

Kcnf1

Potassium voltage-gated channel, subfamily F, member 1

12 A1.1

-1.31

-1.21

ns

NM_172871

Klhl9

Kelch-like 9 (Drosophila)

4 C4

ns

-1.21

-1.31

NM_011945

Map3k1

Mitogen-activated protein kinase kinase kinase 1

13 D2

ns

-1.2

-1.5

BC132343

Mars2

Methionine-tRNA synthetase 2 (mitochondrial)

1 C1

ns

-1.22

-1.62

ENSMUST00000001455

Mef2d

Myocyte enhancer factor 2D

3 F1

-1.21

ns

-1.26

NR_029580

Mir194-1

microRNA 194-1

1

1.22

ns

1.5

NM_028901

Myo18b

Myosin XVIIIb

5 F

1.26

-1.26

ns

NM_153578

Nipa1

Non-imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)

7 C

-1.28

ns

-1.22

NM_001164035

Ntf3

Neurotrophin 3

6 F3

-1.41

ns

-1.58

NM_178668

Pde12

Phosphodiesterase 12

14 A3

ns

-1.22

1.25

NM_009402

Pglyrp1

Peptidoglycan recognition protein 1

7 A3

−1.31

ns

−1.31

NM_001081307

Ppp1r12b

Protein phosphatase 1, regulatory (inhibitor) subunit 12B

1 F

ns

-1.21

-1.29

NM_031499

Prp2

Proline rich protein 2

6 G1

1.68

ns

3.3

NM_029614

Prss23

Protease, serine, 23

7 E1

1.22

-1.21

ns

NM_019566

Rhog

Ras homolog gene family, member G

7 F1

-1.22

1.21

-1.48

NM_146118

Slc25a25

Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25

2 B

-1.21

ns

-1.35

AF357427

Snord115

Small nucleolar RNA, C/D Box 115 cluster

7

ns

1.23

1.71

NR_028275

Snord14e

Small nucleolar RNA, C/D box 14E

9

1.26

-1.27

ns

NM_025291

Sra1

Steroid receptor RNA activator 1

18 B2

-1.27

-1.22

ns

NM_033622

Tnfsf13b

Tumor necrosis factor (ligand) superfamily, member 13b

8 A1

1.21

ns

-1.23

NM_029726

Trdn

Triadin

10 A4

1.27

-1.61

-2.21

BC025894

Ubc

Ubiquitin C

5 G1

ns

1.29

-1.34

NM_016982

Vpreb1

Pre-B lymphocyte gene 1

16 A3

1.46

-1.28

ns

NM_172643

Zbtb41

Zinc finger and BTB domain containing 41 homolog

1 F

-1.22

ns

-1.32

NM_028543

Zfp763

Zinc finger protein 763

17 B1

-1.29

-1.26

ns

  1. aE, embryonic day; P, postnatal day; ns, not significantly different.