Timing of treatmenta | GO category | Functions annotation | P value | Molecules |
---|---|---|---|---|
E 8/11 | Cellular assembly and organization | Extension of axons | 0.0082 | Dclk1, Ntf3, Tnfrsf12a |
 | Protein synthesis | Translation of protein | 0.0025 | Eif2s1, Hspa5 |
 | Cell-to-cell signaling and interaction | Synaptic transmission | 0.0136 | Egr3, Ntf3 |
 | Tissue development | Accumulation of cells | 0.0153 | Cdkn1a, Ntf3 |
 | Cell death | Cell death of sensory neurons | 0.0171 | Hsf1, Ntf3 |
 | Tissue morphology | Quantity of interneurons | 0.0250 | Dclk1, Ntf3 |
E 14/16 | Cellular movement | Migration of interneurons | 0.00013 | Dcx, Dlx1, Dlx2 |
 | Tissue development | Development of olfactory bulb | 0.0168 | Dlx2, Nr2e1 |
 | Cellular development | Differentiation of neuronal progenitor cells | 0.0214 | Dlx1, Dlx2 |
 | Cell death | Cell death of sensory neurons | 0.0238 | Bok, Hsf1 |
 | Neurological disease | Neurodegenerative disorder | 0.0458 | Cav1, Cox1, Dcx, Htr6, Pcna |
 | Cell morphology | Shape change of neurons | 0.0473 | Dcx, Hcrt |
P 4/7 | Cell-to-cell signaling and interaction | Synaptic transmission | 0.00014 | Apoe, Chrm1, Cnr1, Ephb2, Grik1, Grin2b, Htr1a, Nrgn1, Ntf3 |
 | Lipid metabolism | Secretion of steroid | 0.0018 | Apoe, Pomc |
 | Cell-to-cell signaling and interaction | Synaptic depression | 0.0133 | Chrm1, Cnr1, Ephb1, Grin2b, Htt |
 | Cell-to-cell signaling and interaction | Plasticity of synapse | 0.0144 | Apoe, Grik1, Grin2b, Htt, Inppl1, Syngap1 |
 | Cell morphology | Formation of cellular protrusions | 0.0329 | Apoe, Dst, Efna5, Efnb2, Egfr, Ephb1, Grm4, Htt, Kif23, Nbl1, Ntf3, Ntng2, Pcdh15, Rhog, Syne1, Syngap1, Wnt3a |
 | Cellular development | Proliferation of neuronal cells | 0.0366 | Cnr1, Irx5, Mycn, Nbn, Ntf3, Wnt3a |
 | Neurological disease | Gliosis of hippocampus | 0.0400 | Apoe, Htt |