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Table 1 Patient sample description

From: A pilot open-label trial of minocycline in patients with autism and regressive features

Subject

Pretreatment age (months)

Sex

Age at onset of regression (months)

Clinical assessment

Non-verbal IQ/DQ

CGI- baseline

CGI- post-treatment

Vineland- ABC baseline

Vineland-ABC post-treatment

1

99

F

27

30

6

5

55

54

2a

64

M

13

60

5

4a

68

73a

3

69

M

12

33

5

5

45

44

4

153

M

19

77

5

5

56

55

5

91

M

8

58

3

3

60

56

6

66

M

18

103

4

4

70

71

7

128

F

15

25

5

5

55

46

8

112

M

14

33

5

5

53

56

9

49

M

18

59

4

4

66

63

10

38

M

22

90

4

3

70

66

11

83

M

18

32

5

5

48

57

    

M ± SD

4.6 ± 0.8

4.4 ± 0.8

58.7 ± 8.8

58.3 ± 9.3

    

Effect Size

-

−0.3

-

−0.1

  1. aDenotes child that discontinued the study at 3 months.
  2. Note: Effect size was calculated for the within-subjects effect using the following formula: ES = (MPost - MBL)/SDBL). CGI, Clinical Global Impression.