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Table 1 Patient sample description

From: A pilot open-label trial of minocycline in patients with autism and regressive features

Subject Pretreatment age (months) Sex Age at onset of regression (months) Clinical assessment
Non-verbal IQ/DQ CGI- baseline CGI- post-treatment Vineland- ABC baseline Vineland-ABC post-treatment
1 99 F 27 30 6 5 55 54
2a 64 M 13 60 5 4a 68 73a
3 69 M 12 33 5 5 45 44
4 153 M 19 77 5 5 56 55
5 91 M 8 58 3 3 60 56
6 66 M 18 103 4 4 70 71
7 128 F 15 25 5 5 55 46
8 112 M 14 33 5 5 53 56
9 49 M 18 59 4 4 66 63
10 38 M 22 90 4 3 70 66
11 83 M 18 32 5 5 48 57
     M ± SD 4.6 ± 0.8 4.4 ± 0.8 58.7 ± 8.8 58.3 ± 9.3
     Effect Size - −0.3 - −0.1
  1. aDenotes child that discontinued the study at 3 months.
  2. Note: Effect size was calculated for the within-subjects effect using the following formula: ES = (MPost - MBL)/SDBL). CGI, Clinical Global Impression.