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Table 2 Reported health problems during minocycline treatment

From: A pilot open-label trial of minocycline in patients with autism and regressive features

Subject

URI a

GI b

Others

1

X

 

Hematuria, weight gain, hyperactivity, urinary tract infection

2c

X

 

Increased aggression and head-banging, c/o head hurting

3

 

X

Otitis media

4

X

 

Epistaxis, increased sensitivity to lights

5

X

X

Increased aggression

6

X

  

7

  

Teeth staining; increased appetite, aggression and ritualistic behavior, weight gain, PICA

8

X

X

Microscopic hematuria

9

 

X

 

10

X

X

 

11

X

X

 
  1. aURI, Upper respiratory infection symptoms.
  2. bGI, Gastrointestinal symptoms included nausea, vomiting, and/or diarrhea on at least one occasion.
  3. cSubject withdrew at three months.