Self-injury and aggression in tuberous sclerosis complex: cross syndrome comparison and associated risk markers

Table 2 Rates of self-injury and aggression compared between Down syndrome and other syndromes, including TSC

	Self-injurious behaviour		Aggression
Syndrome group	%	Odds ratio between syndrome groups (99% confidence intervals)	%	Odds ratio between syndrome groups (99% confidence intervals)
Down syndrome (comparison group)	11.90^a	–	40.50^a	–
Tuberous sclerosis complex	27.00	2.74 (0.58 to 13.00)	50.00^a	1.47 (0.45 to 4.80)
Cornelia de Lange syndrome	63.90	13.12 (3.21 to 53.66)	44.10^b	1.16 (0.40 to 3.33)
Fragile X syndrome	54.50	8.85 (2.36 to 33.24)	60.90^b	2.29 (0.88 to 5.95)
Autism spectrum disorder	41.70^a	5.30 (1.46 to 19.19)	66.70^c	2.94 (1.19 to 7.29)

^aData missing for one participant; ^bData missing for two participants; ^cData missing for eight participants; Bold text indicates significantly greater risk of challenging behaviour in test group compared with Down syndrome comparison group (P < 0.01).

ISSN: 1866-1955