Figure 3
From: The multiple molecular facets of fragile X-associated tremor/ataxia syndrome
Expression of the minor splice isoform in the ASFMR1 transcript (131 bp), located near the ASFMR1 promoter. Expression of this isoform increases in premutation carriers (P < 0.001), and shows a similar trend in subjects with intermediate alleles (P = 0.0528) compared with normal alleles. The solid blue line on the plot shows a piecewise linear regression fit (fitted on the log scale then exponentiated for plotting), with separate slopes in the normal, intermediate, and premutation alleles.