Testing for association of the monoamine oxidase A promoter polymorphism with brain structure volumes in both autism and the fragile X syndrome

Table 2 Brain structure volumes by diagnosis and genotype

	All subjects		Autism only		FXS - ASD		FXS + ASD
	High	Low	High	Low	High	Low	High	Low
	(n = 51)	(n = 30)	(n = 21)	(n = 13)	(n = 20)	(n = 10)	(n = 10)	(n = 7)
Total brain volume	1261 ± 96	1330 ± 99	1271 ± 100	1334 ± 88	1246 ± 111	1338 ± 137	1254 ± 88	1315 ± 86
Frontal gray	246 ± 24	261 ± 18	251 ± 24	266 ± 16	238 ± 25	258 ± 23	243 ± 23	255 ± 16
Frontal white	105 ± 11	114 ± 11	107 ± 11	116 ± 8.2	104 ± 15	113 ± 16	104 ± 11	110 ± 8.8
Temporal gray	155 ± 13	165 ± 15	157 ± 13	168 ± 16	151 ± 14	163 ± 17	153 ± 14	162 ± 12
Temporal white	43.4 ± 4.7	46.8 ± 5.5	41.5 ± 3.6	45 ± 4.9	45.2 ± 5.5	47.9 ± 6.3	44.5 ± 4.9	50.9 ± 5.5
Parietal-occipital gray	252 ± 22	265 ± 20	253 ± 25	266 ± 15	249 ± 18	266 ± 32	251 ± 20	262 ± 16
Parietal-occipital white	101 ± 10	108 ± 9.3	103 ± 10	109 ± 8	99 ± 8.9	108 ± 14	99 ± 9.5	106 ± 6.5

ISSN: 1866-1955