Figure 1

Fear conditioning tests in PERM-treated and control groups. A) Locomotor activity, expressed as distance moved, during 3-minute habituation period preceding the conditioning session. B) Freezing on conditioning session expressed as 1-minute averages for the period before (baseline) and after each of ten tone-shock conditioning trials. C) Freezing on context (CX) and cued (CS) fear conditioning sessions during an 8-minute extinction test. All data are means ± SEM. Group sizes: control (N = 13), PERM (N = 15). *P < 0.05 versus control group; **P < 0.01 versus control group; ***P < 0.001 versus control group.