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Table 1 Indices of thermal nociceptive sensitivity (tail-flick latency and hot-plate latency), locomotor activity (number total ambulatory, stereotypic and rearing counts) and anxiety-like behavior (percent ambulatory counts, percent stereotypic and rearing counts in central zone, percent time in open arm and percent open arm entries) measured in control and permethrin (PERM)-treated groups

From: Neonatal exposure to permethrin pesticide causes lifelong fear and spatial learning deficits and alters hippocampal morphology of synapses

Test

Parameter

Number of animals

Control group

PERM group

Tail immersion

Tail flick latency (s)

13 control

4.42 ± 0.32

5.47 ± 0.41

15 PERM

Hot-plate

Hot-plate latency (s)

13 control

2.73 ± 0.32

2.43 ± 0.17

15 PERM

Open field

Number of total ambulatory counts

10 control

3,374.80 ± 193.13

3,039.40 ± 170.89

10 PERM

 

Number of total stereotypic counts

 

1,350.89 ± 156.67

1,714.60 ± 133.95

 

Number total rearing counts

 

167.80 ± 13.62

198.30 ± 10.65

 

Percent ambulatory counts in central zone

 

4.54 ± 0.68

5.04 ± 0.32

 

Percent stereotypic counts in central zone

 

1.43 ± 0.37

3.35 ± 0.83

 

Percent rearing counts in central zone

 

3.47 ± 0.80

3.88 ± 0.44

Elevated plus maze

Percent time in open arm

10 control

49.99 ± 2.97

51.91 ± 3.28

10 PERM

 

Percent open arm entries

 

41.97 ± 2.93

40.83 ± 2.04