Test | Parameter | Number of animals | Control group | PERM group |
---|---|---|---|---|
Tail immersion | Tail flick latency (s) | 13 control | 4.42 ± 0.32 | 5.47 ± 0.41 |
15 PERM | ||||
Hot-plate | Hot-plate latency (s) | 13 control | 2.73 ± 0.32 | 2.43 ± 0.17 |
15 PERM | ||||
Open field | Number of total ambulatory counts | 10 control | 3,374.80 ± 193.13 | 3,039.40 ± 170.89 |
10 PERM | ||||
 | Number of total stereotypic counts |  | 1,350.89 ± 156.67 | 1,714.60 ± 133.95 |
 | Number total rearing counts |  | 167.80 ± 13.62 | 198.30 ± 10.65 |
 | Percent ambulatory counts in central zone |  | 4.54 ± 0.68 | 5.04 ± 0.32 |
 | Percent stereotypic counts in central zone |  | 1.43 ± 0.37 | 3.35 ± 0.83 |
 | Percent rearing counts in central zone |  | 3.47 ± 0.80 | 3.88 ± 0.44 |
Elevated plus maze | Percent time in open arm | 10 control | 49.99 ± 2.97 | 51.91 ± 3.28 |
10 PERM | ||||
 | Percent open arm entries |  | 41.97 ± 2.93 | 40.83 ± 2.04 |