Differences in age-related effects on brain volume in Down syndrome as compared to Williams syndrome and typical development

Table 2 Brain regions where the relationship between age and volume was significantly different between participants with Down syndrome (DS) versus typical development (TD)

Region of interest	Group (DS versus TD) × Age Interaction
Region of interest	t	P-value	Difference in R²
LILV	4.31	3.25E-05	0.09
RILV	4.05	9.03E-05	0.10
Left superior parietal	-4.02	1.01E-04	0.08
Left inferior parietal	-3.97	1.23E-04	0.08
Left pars orbitalis	-3.82	2.11E-04	0.07
Right post central gyrus	-3.67	3.58E-04	0.07

Difference in R² is reported for full model that included age, sex, group and groupxage, versus the reduced model that included age, sex, and group.

ISSN: 1866-1955