| |
22q11DS
|
Control
|
p
value
|
|---|
| |
n = 14
|
n = 14 (9)
| |
|---|
|
Age range (mean ± SD)
|
9–17 (13 ± 2)
|
8–17 (13 ± 3)
|
0.942
|
|---|
|
Sex: M/F
|
7/7
|
9(5)/5(4)
| |
|
FSIQ (WISC-III)
|
66 ± 7
|
114 ± 16
|
0.000**
|
|
PIQ (WISC-III)
|
67 ± 8
|
108 ± 19
|
0.000**
|
|
VIQ (WISC-III)
|
70 ± 12
|
111 ± 16
|
0.000**
|
|
ASQ
|
n = 12
|
n = 8
| |
| |
6 ± 4
|
2 ± 3
|
0.048*
|
|
ADHD index
|
n = 11
|
n = 9
| |
| |
60 ± 10
|
48 ± 5
|
0.039*
|
|
SDQ
|
n = 11
|
n = 9
| |
|
Total difficulties
|
13.9 ± 7.1
|
6.2 ± 4.1
|
0.011*
|
|
Emotional symptoms
|
3.6 ± 3.3
|
0.7 ± 0.7
|
0.117*
|
|
Conduct problems
|
2.1 ± 1.6
|
1.6 ± 1.6
|
0.471
|
|
Hyperactivity
|
5.2 ± 3.3
|
3.2 ± 2.9
|
0.182
|
|
Peer problems
|
3 ± 2.7
|
0.8 ± 1.4
|
0.040*
|
|
Prosocial behavioura
|
7.9 ± 1.6
|
8.6 ± 1.4
|
0.354
|
|
Gender discrimination task
| | | |
|
Fear accuracy
|
73 ± 20
|
83 ± 17
|
0.15
|
|
Fear response time
|
771 ± 212
|
842 ± 109
|
0.279
|
|
Disgust accuracy
|
81 ± 9
|
83 ± 17
|
0.606
|
|
Disgust response time
|
883 ± 139
|
840 ± 126
|
0.408
|
- Accuracy and response time for the gender discrimination task for 22q11DS group and the controls. ADHD index which is a subscale of the ‘Conners Rating Scales’ (CRS).
-
FSIQ full scale IQ, PIQ performance IQ, VIQ verbal IQ, ASQ Autism Screening Questionnaire, SDQ Strengths and Difficulties Questionnaire.
-
*Significant at a trend level p < 0.05; **significant at p < 0.001; areverse scale.
