Psychopathology and cognitive performance in individuals with membrane-associated guanylate kinase mutations: a functional network phenotyping study

Table 1 Study participants

Demographic measure		Gene functional group		*P value*
Demographic measure		MAGUK ( n = 9)	XLID ( n = 17)	*P value*
Age at assessment/years	range	13.4 to 40.4	6.2 to 54	0.28
Age at assessment/years	mean (SD)	24.5 (9.2)	30.4 (14.3)	0.28
Gross motor ability^a	range	1 to 16	1 to 16	0.11
Gross motor ability^a	mean (SD)	10.6 (5.0)	7.2 (4.7)	0.11
Global intellectual ability^b	range	20 to 61	20 to 67	0.40
Global intellectual ability^b	mean (SD)	44 (14)	38 (18)	0.40
Mild or moderate impairment	% within functional group	66.7	41.2	0.22
Severe or profound impairment	% within functional group	33.3	58.8	0.22
History of seizures	% within functional group	11.1	35.3	0.19

^aVineland age-appropriate standard score; ^bVineland Adaptive Behaviour Composite standard score, general population mean 100.

ISSN: 1866-1955