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Table 3 Between-group differences in the social negative reinforcement condition

From: Neural mechanisms of negative reinforcement in children and adolescents with autism spectrum disorders

 

MNI coordinates

Brain region

Voxels

Z (max)

X

Y

Z

L amygdala/putamen

29

4.57

20

−6

−12

R Anterior cingulate cortexa

21

3.66

8

22

30

R frontal pole

101

4.25

42

50

4

R inferior frontal gyrus, pars opercularis

23

3.98

60

14

6

L insula

26

4.51

−34

14

−2

R insula/orbital frontal cortexa

99

4.67

38

20

2

R putamen/nucleus accumbens/caudate nucleus

248

5.26

24

6

6

  1. aTwo clusters within same region, coordinates, and peak activation reported for highest peak activation. All coordinates (x, y, z) are given in MNI space. L, left, R, right. Clusters with decreased activation in the ASD group relative to the control group for the anticipation of sad faces (thresholded at Z > 3.0, cluster-corrected significance threshold of P < .05).