Table 2 Cognitive development least square means group comparisons at 6, 12, and 24 months
Cognitive development | HR-ASD-High (a) | HR-ASD-Mod (b) | HR-Neg (c) | LR-Neg (d) | Overall Group Comparisona | Post hoc comparisonsb | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
(n = 31) | (n = 18) | (n = 161) | (n = 98) | ||||||||||
LSM | SE | LSM | SE | LSM | SE | LSM | SE | df1 | df2 | F | p | ||
6 Month visit | |||||||||||||
MSEL ELC | 93.9 | 1.9 | 98.3 | 2.4 | 98.4 | 0.8 | 100.5 | 1.1 | 3 | 299 | 3.2 | 0.02 | |
Expressive Language | 42.9 | 1.3 | 46.6 | 1.6 | 44.5 | 0.5 | 46.5 | 0.7 | 3 | 299 | 3.0 | 0.03 | |
Receptive Language | 49.6 | 1.6 | 47.9 | 2.1 | 49.9 | 0.7 | 50.0 | 0.9 | 3 | 299 | 0.3 | 0.83 | |
Fine Motor | 47.8 | 1.7 | 51.2 | 2.1 | 50.4 | 0.7 | 50.2 | 1.0 | 3 | 299 | 0.7 | 0.54 | |
Gross Motor | 43.7 | 1.5 | 46.3 | 2.0 | 49.0 | 0.7 | 50.8 | 0.9 | 3 | 299 | 5.8 | 0.0007 | a < d |
Visual Reception | 47.3 | 1.6 | 50.5 | 2.0 | 51.4 | 2.0 | 53.9 | 0.9 | 3 | 299 | 4.8 | 0.0028 | a < d |
12 Month visit | |||||||||||||
MSEL ELC | 89.2 | 2.3 | 93.8 | 3.1 | 101.2 | 1.0 | 105.5 | 1.3 | 3 | 299 | 14.5 | <0.0001 | a < (c, d) |
Expressive Language | 39.5 | 2.0 | 37.7 | 2.8 | 47.2 | 0.9 | 49.6 | 1.1 | 3 | 299 | 10.0 | <0.0001 | (a, b) < d |
Receptive Language | 36.1 | 1.5 | 39.4 | 2.0 | 43.5 | 0.6 | 45.6 | 0.8 | 3 | 299 | 11.2 | <0.0001 | a < (c, d) |
Fine Motor | 53.9 | 1.7 | 57.9 | 2.3 | 57.0 | 0.7 | 59.6 | 0.7 | 3 | 299 | 3.4 | 0.02 | |
Gross Motor | 42.7 | 2.2 | 45.6 | 3.0 | 49.7 | 1.0 | 50.4 | 1.2 | 3 | 299 | 3.7 | 0.01 | |
Visual Reception | 47.6 | 1.7 | 51.4 | 2.3 | 54.3 | 0.7 | 55.6 | 0.9 | 3 | 299 | 6.2 | 0.0004 | a < d |
24 Month visit | |||||||||||||
MSEL ELC | 75.8 | 3.0 | 84.1 | 3.9 | 103.1 | 1.3 | 109.4 | 1.7 | 3 | 299 | 38.0 | <0.0001 | (a, b) < (c, d) |
Expressive Language | 36.1 | 2.1 | 39.1 | 2.7 | 49.0 | 0.9 | 51.7 | 1.2 | 3 | 299 | 18.3 | <0.0001 | a < (c, d), b < d |
Receptive Language | 31.1 | 2.0 | 38.8 | 2.6 | 51.9 | 0.9 | 56.0 | 1.1 | 3 | 299 | 44.9 | <0.0001 | (a, b) < (c, d) |
Fine Motor | 39.9 | 1.7 | 42.9 | 2.3 | 49.9 | 0.8 | 54.6 | 1.0 | 3 | 299 | 21.6 | <0.0001 | a < (c, d), (b, c) < d |
Gross Motor | 38.4 | 1.6 | 43.9 | 2.1 | 50.2 | 0.7 | 52.0 | 0.9 | 3 | 299 | 19.8 | <0.0001 | a < (c, d) |
Visual Reception | 39.9 | 2.0 | 45.0 | 2.6 | 54.9 | 0.9 | 55.9 | 1.1 | 3 | 299 | 20.4 | <0.0001 | a < (c, d), b < d |