Behavioral, cognitive, and adaptive development in infants with autism spectrum disorder in the first 2 years of life

Table 4 Autism behaviors longitudinal response profile and least square means by group at 6 and 12 months

AOSI total score	HR-ASD-High (a)		HR-ASD-Mod (b)		HR-Neg (c)		LR-Neg (d)		Overall Group Comparison^a				Post hoc comparisons^b
	(n = 31)		(n = 18)		(n = 161)		(n = 98)		Overall Group Comparison^a
	LSM	SE	LSM	SE	LSM	SE	LSM	SE	df₁	df₂	F	p
6 Month visit	10.6	0.7	10.1	0.9	9.7	0.3	8.2	0.4	3	293	4.1	0.0068
12 Month visit	9.3	0.7	7.9	0.9	5.1	0.3	4.4	0.4	3	293	15.8	<0.0001	a < (c, d)

^aThe Overall Group Comparison serves as an omnibus test comparing the means between the four groups to determine whether group means differ based on a mixed model with repeated measures. Model covariates included the difference between the child’s actual age at the visit from the scheduled visit age (6 and12 months). Other covariates included site and mother’s education. Two-sided at significance level of .05
^bPost hoc comparisons with step-up Bonferroni correction. Two-sided at significance level of .05

ISSN: 1866-1955