Atypical functional connectivity in resting-state networks of individuals with 22q11.2 deletion syndrome: associations with neurocognitive and psychiatric functioning

Table 1 Demographic and medical data

	22q11DS	Controls	P value
	N = 55	N = 29	P value
Age^a	20.42 (2.31)	20.46 (1.41)	0.923
Gender (male, %)	27 (49.1 %)	17 (58.6 %)	0.412
Full scale IQ^a	73.35 (10.51)	109.45 (9.72)	<0.001
Psychiatric diagnosis, n (%)
Psychotic disorder	5 (9.10 %)	0 (0 %)	0.024
ADHD	9 (16.36 %)	3 (10.34 %)	0.460
Anxiety disorder	15 (27.27 %)	3 (10.34 %)	0.046
Mood disorder	9 (16.36 %)	1 (3.45 %)	0.037
Current medication, n (%)
Antipsychotic/mood stabilizer	7 (12.73 %)	0 (0 %)	0.007
Antidepressant/antianxiety	18 (32.73 %)	1 (3.45 %)	<0.001
Stimulants	6 (10.91 %)	2 (6.90 %)	0.557

Demographic and medical data for participants in our group analyses; from our initial sample of 87, 2 patients were excluded due to image quality or age and 1 control was excluded due to lack of neuropsychological data
^aMean and standard deviation are provided for age and full scale IQ. Independent t tests were conducted to determine differences between 22q11DS and control samples. Demographics did not differ across sites. Additional information can be found in Additional file 1: Table S1

ISSN: 1866-1955