Fig. 3

Predicted 8-mer binding sites for LHX2 in the genomic area of SNV4. The reference sequence (shown on the top row) was scanned for 8-mer binding profiles for transcription factors from the UniPROBE database [33]. The rows below the reference sequence show predicted 8-mer binding sites for LHX2, so that the bases that are not included in the 8-mer are shown in grey. The enrichment scores from the protein binding microarray data are shown rightmost on each row. The TAATTA consensus site for homeobox is shown in green, and the reference allele (cytosine) at SNV4 is shown in red. The alternative allele (thymidine) is shown in blue