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Table 1 Overview of the behavioral tests per batch

From: Limited impact of Cntn4 mutation on autism-related traits in developing and adult C57BL/6J mice

Age

Task

Batch

Subjects (n)

3 weeks

Juvenile social interaction

Batch 1 + 2

6–7 genotype-matched pairs per genotype

4 weeks

Extended SHIRPA screen

Batch 1 + 2

19–26 per genotype

6 weeks

Extended SHIRPA screen

Batch 1 + 2

19–26 per genotype

8 weeks

Extended SHIRPA screen

Batch 1 + 2

19–26 per genotype

Adult

Extended SHIRPA screen

Batch 1

10–15 per genotype

 

Open field

Batch 1

10–15 per genotype

 

Elevated plus maze

Batch 1

10–15 per genotype

 

Social discrimination

Batch 1

10–15 per genotype

 

Buried food test

Batch 2

9–11 per genotype

 

Set shifting-reversal task

Batch 2

9–11 per genotype

 

Social approach in 3-chamber

Batch 3

12 per genotype

 

Novel object exploration task

Batch 3

12 per genotype

 

Barnes maze-reversal task

Batch 4

16 per genotype

 

Pre-pulse inhibition

Batch 4

16 per genotype

  1. Animals in batch 1 + 2 were weaned at post-natal day 21. Batch 3 + 4 animals were weaned at post-natal day 28