Fig. 1

Developmental age-equivalents (DAE) (a) and developmental quotients (DQs) (b) of children with 22q13.3 deletions. Data based on Bayley-III-NL (n = 33) and WPPSI-III-NL (n = 1) results for cognition. The dashed line represents the normal relation between DAE and age in typically developing children. Terminal deletion terminal deletion not caused by ring chromosome formation. Mosaic deletion (individual 7), additional CNV additional copy number variation (individuals 5,16, 28), S small deletion including only SHANK3, ACR, and RABL2B (individuals 10, 17, 18, 31)