Fig. 1
From: Effects of early-life exposure to THIP on phenotype development in a mouse model of Rett syndrome
THIP administration extended the lifespan of MECP2-null mice. a Twenty-nine MECP2-null mice were used in the survival experiment and 14 of them were delivered THIP orally (solid line) and 13 without THIP treatment (dashed line). (**P < 0.01; Mantel-Cox test). b Percentage of survival in the tested mice. In the vehicle group, 50 % MECP2-null mice died within 52 days, while THIP treatment expanded the 50 % lifespan to 82 days