Skip to main content


Fig. 7 | Journal of Neurodevelopmental Disorders

Fig. 7

From: Effects of early-life exposure to THIP on phenotype development in a mouse model of Rett syndrome

Fig. 7

Alteration of GABAAR subunits in the LC area of MECP2-null mice. qPCR analysis indicated that the mRNA levels of δ and α6 subunits were 2.0 and 3.5 times higher than the WT levels, while THIP treatment significantly reduced the expression level of α6 subunit, without alteration of δ, β1, and β2 subunits (vehicle: n = 4 and n = 4 animals; THIP: n = 5 and n = 5 animals; WT and MECP2-null, respectively; **P < 0.01; Student’s t test)

Back to article page