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Table 4 Linear models for negative and positive symptoms: the effect of social function, skills, and cognition adjusted for age, sex, and IQ

From: Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome

  

Negative symptoms

Positive symptoms

 

Model

ABAS

SRS

TASIT

ERT

ABAS

SRS

TASIT

Intercept

Estimate

3.90

3.55

3.66

4.18

2.17

1.81

1.95

T

4.90

4.34

4.22

4.17

1.73

1.37

1.45

Pr(>|t|)

6.76 × 10−5

0.0003

0.0003

0.0004

0.1

0.18

0.16

Age

Estimate

0.04

0.06

0.03

−0.01

0.17

0.19

0.11

T

0.88

1.25

0.71

−0.20

2.20

2.23

1.43

Pr(>|t|)

0.39

0.22

0.48

0.84

0.04

0.04

0.17

Male sex

Estimate

−0.35

−0.05

0.02

0.002

−1.18

−0.82

−0.54

T

−1.21

−0.21

0.08

0.006

−2.61

−1.98

−1.37

Pr(>|t|)

0.24

0.84

0.94

0.99

0.02

0.06

0.18

IQ

Estimate

−0.02

−0.03

−0.02

−0.02

−0.03

−0.03

−0.02

T

−3.09

−3.33

−2.94

−2.16

−2.63

−2.70

−2.03

Pr(>|t|)

0.005

0.003

0.007

0.04

0.02

0.01

0.05

Social measure

Estimate

−0.51

0.52

−0.38

−0.19

−0.64

0.63

−0,25

t

−3.67

3.78

−2.86

−1.23

−2.93

2.89

−1.18

Pr(>|t|)

0.001

0.001

0.009

0.23

0.008

0.009

0.25

Full modela

Rb

0.42

0.44

0.39

0.22

0.29

0.28

0.15

F (df)

5.71 (4,22)

5.93 (4,21)

5.28 (4,23)

2.92 (4,23)

3.60 (4,22)

3.47 (4,21)

2.17 (4,23)

P

0.003

0.001

0.004

0.04

0.02

0.03

0.10

Basica vs. full modelb

F

13.44

14.31

8.18

1.51

8.59

8.38

1.38

p

0.001

0.001

0.009

0.23

0.008

0.009

0.25

  1. aFull model: SIPS score = age + sex + IQ + social measure (i.e., ABASsocial, SRStotal, TASITtotal, or ERTtotal)
  2. bBasic model: SIPS score = age + sex+ IQ