Fig. 5

Neural correlates of disruptive behavior on the contrast of DMN deactivation (fixation > BIO) in ASD. Disruptive behavior was based on oppositional defiant disorder (ODD) scores, without controlling for Social Responsiveness Scale (SRS) total raw scores. Left panel illustrates the brain regions showing significant correlates. Right panel is the scatterplot of disruptive behavior (x-axis) and the average DMN deactivations to fixation > BIO in these brain regions (y-axis; unit: percent signal change), with a regression line and the 95% confidence intervals. DMN, default mode network; BIO, biological motion; MPFC, medial prefrontal cortex; LPC, lateral parietal cortex. ****p < 0.0001