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Table 3 Peaks of regions in which the contrast of social perception (BIO > SCR) exhibited TD > ASD group differences

From: Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder

  

TD > ASDAll

TD > ASDLow-ODD

TD > ASDHigh-ODD

Anatomical regions

 

x

y

z

Z

x

y

z

Z

x

y

z

Z

Angular gyrus

R

34

−60

42

3.09

    

34

−58

42

4.13

Fusiform gyrus

R

34

−44

−4

2.72

42

−54

−16

2.56

34

−44

−4

2.82

Hippocampus

R

36

−34

−4

3.11

        

Inferior occipital gyrus

R

52

−78

−4

3.60

46

−86

−2

3.61

    

Middle occipital gyrus

R

38

−92

8

4.38

44

−88

6

4.35

34

−62

38

2.87

Inferior parietal gyrus

R

38

−54

40

2.71

    

36

−54

42

3.38

Supramarginal gyrus

R

        

38

−42

42

3.06

Inferior temporal gyrus

R

58

−64

−14

3.93

58

−64

−14

3.68

42

−58

−8

3.15

Middle temporal gyrusa

R

56

−72

0

3.95

56

−72

0

3.97

44

−68

16

3.37

  1. Coordinates are in MNI152 mm space. Results were thresholded at Z > 1.96 (p < 0.05) and corrected for multiple comparisons at the cluster level (p < 0.05)
  2. R right, BIO biological motion, SCR scrambled motion, ODD oppositional defiant disorder
  3. aThe hypoactivation in the right posterior superior temporal sulcus (pSTS) was detected in all these three comparisons (see Fig. 2). Because the right pSTS is not one of the pre-defined anatomical regions of the AAL2 atlas, it was not listed here. In our results, the hypoactivation in the right pSTS was primarily in the anatomical region of the right middle temporal gyrus