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Table 7 Peaks of regions where ADHD and anxiety symptoms mediated the link between disruptive behavior and less DMN deactivation in ASD

From: Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder

Mediator

Anatomical regions

 

x

y

z

Z

Anxiety symptoms

Anterior cingulate and paracingulate gyri

L

−10

38

10

3.11

  

R

6

38

28

2.67

 

Middle cingulate and paracingulate gyri

R

2

36

30

2.63

 

Superior frontal gyrus, medial

L

−2

38

28

2.69

  

R

4

42

32

2.63

ADHD symptoms

Anterior cingulate and paracingulate gyri

L

2

38

14

3.16

  

R

6

38

28

2.39

 

Middle cingulate and paracingulate gyri

R

2

36

30

2.76

 

Superior frontal gyrus, medial

L

2

34

32

2.78

  1. Coordinates are in MNI152 mm space. Results were thresholded at Z > 1.96 (p < 0.05) and corrected for multiple comparisons at the cluster level (p < 0.05)
  2. L left, R right, DMN default mode network